Memoractiv

Volume

60 capsules

Memorectv is a nutritional supplement that helps improve cognitive ability and memory by containing only high-quality nutrients such as vinpocetine and ginkgo, which improve blood circulation, and carnitine, which helps strengthen concentration and memory.

It also contains phosphatidylserine (PS, Phosphatidylserine), a substance that helps memory and brain health by maintaining the health of brain cell membranes.



PS is widely known in the United States and Europe as a substance that promotes nerve transmission, improves memory and learning ability, prevents dementia, improves attention deficit, and has antidepressant effects. The U.S. Food and Drug Administration (FDA) allows health functional foods containing PS (phosphatidylserine) to be labeled as 'possible to reduce the risk of cognitive decline and dementia in the elderly.' It became even more famous when former U.S. President Ronald Reagan took it along with his dementia treatment when he was suffering from Alzheimer's dementia.



If we look at how PS exerts its efficacy in preventing memory decline and improving dementia, it can be summarized in three aspects as follows.





1. Action on the structural aspect of the brain



1) The main structural effect of PS is in the regulation of membrane fluidity. As the brain ages, membrane fluidity decreases, enzyme activity and membrane transport mechanisms decrease, and brain functions such as learning ability and memory are impaired. Through animal experiments, PS is known to be incorporated into brain synaptosomes and increase fluidity by controlling membrane fluidity through regulation of enzymes such as (Na+/K+)-stimulated ATPase and acetylcholinesterase. It has been reported that periodic supply of PS restores the ideal ratio of aged animals to the normal level of young animals, improving the fluidity and composition of biological membranes.


▶ Phosphatidylserine restores brain function by restoring the decrease in fluidity of brain cell membranes caused by brain aging.






2) It is reported that the brain has a decrease in cholinergic neurons and dendrites of hippocampal nerves due to aging, which means loss of synapses. Loss of synapses has been proven to be related to memory. It has been reported that periodic treatment of PS in rats prevents the concentration of dendrites in the hippocampus from decreasing with age.




▶ Prevents memory loss by preventing and restoring synapses and neurons, the source of memory, from aging due to brain aging.


2. Neurotransmission activities in the brain


1) Memory loss due to aging may be caused by a lack of neurotransmitters. In particular, it is known that degenerative changes in neurons within the brain, especially cholinergic neurons, are correlated with the degree of cognitive impairment. The actions of dopamine, glutamate, and acetylcholine are known to play essential roles in learning, memory, and other cognitive functions in humans.



Specifically, phosphatidylserine maintains an appropriate level of acetylcholine by maintaining the supply of the neurotransmitter acetylcholine or promoting the synthesis and release of acetylcholine. Phosphatidylserine restores the release of dopamine, a neurotransmitter stimulated by the action of glutamic acid. It is also known to help maintain neuron action and intracellular message transmission by activating protein kinase C, tyrosine hydroxylase, acetylcholine esterase, and ATPase, which are enzymes that form the signal transmission cascade by neurotransmitters within neuron cells.



In addition, PS plays a role in restoring the decrease in various receptors in the brain. For example, it is reported that it increases the number of NMDA receptors by about 25% and normalizes the affinity of glutamate for these receptors.


▶ It improves brain function by promoting the supply and delivery of neurotransmitters that are important for brain memory function.




3. Actions in nerve growth factor-related aspects
PS prevents the loss of NGF (Nerve growth factor) receptors in the hippocampus due to aging and increases the synthesis and release of NGF. It also stimulates the development and growth of neural neurons, and this action ultimately improves learning ability and memory decline. It can help you do that.


▶ PS promotes the synthesis and release of nerve growth factors and improves brain function.



It helps prevent and treat dementia and brain diseases, and is an effective product despite its high price.